Below is a National Institute of Health (NIH) meeting abstract of results obtained using gallium nitrate to inhibit HIV-1 replication in vitro. As you read this abstract, consider that gallium nitrate might be a useful anti-HIV agent for preventing and treating HIV infection and saving lives. This material is for education purposes only, and it is not a "proven" preventative or cure for HIV/AIDS. Condoms are always recommended, but too many people go bareback, thus this treatment/preventative may be life-saving to them.

BACKGROUND: Gallium nitrate (Ga) is a potent ribonucleotide reductase inhibitor which was previously shown to inhibit avian retroviruses. Although the mechanism of its anti-retroviral activity was not elucidated, it is known that Ga inhibits cellular activation in a manner analogous to hydroxyurea (HU). Since Ga is administered to humans intravenously, and oral preparations are being developed, we evaluated Ga for its anti-HIV activity, and compared it with HU. METHODS: Various concentrations of Ga or HU were added to 1 x 106 PHA/IL2 stimulated PBMC's 24 hours prior to infection with HIV-1 stock virus. 16 hrs. following infection, cells were washed and culture supernatants were obtained 4 and 7 days post-infection. HIV p24 antigen production in culture supernatants was determined by ELISA. To determine if RT inhibitors were potentiated by Ga, zidovudine(zdv), ddI and ddC were also evaluated with and without Ga. RESULTS: Ga reproducibly inhibited HIV replication at concentrations which did not inhibit cellular proliferation or viability. Ga IC50 ranged from 4 to 10 micromolar, which was approximately 15-fold lower than HU (120 micromolar) in our culture system. Using sub-inhibitory concentrations of zdv, ddI and ddC, Ga potentiated the inhibitory effects of these nucleoside analogs. The addition of transferrin to the cell culture did not appear to have a significant effect on the antiviral activity of Ga. CONCLUSIONS: Ga was considerably more potent than HU in inhibiting HIV-1 replication in stimulated PBMC culture. This effect potentiated the effect of anti-HIV nucleoside RT inhibitors. Ga inhibits the same cellular target as HU although it does so by a different mechanism of action. Since the inhibitory concentration of Ga is achievable in humans, and the relative potency of Ga is greater than HU, additional studies of Ga appear warranted. Blood levels of gallium need to reach 0.10 millimolar (100 micromolar) to be inhibitory, which is a measurement that medical laboratory clinics could determine through blood tests.

The above abstract is located here: Gallium Nitrate: a Potent Inhibitor of HIV-1 Infection In Vitro.

INTERESTING! I noticed that Stapleton had filed a patent on his discovery, and it is located here. Perhaps the most important point made in his patent is shown in this figure. Gallium inhibits HIV-1 replication, especially when its concentration is 100 micromolar or more, which is equivalent to 0.1 millimolar. Others have filed similar patents, like this one by Bernstein. They each say that gallium inhibits HIV-1 replication. Additionally, gallium nitrate potentiates the effects of NRTIs such as didexoyinosine, dideoxycytidine and azidothymidine.

COMMENT: The above abstract on the National Library of medicine/ National Institute of Health website and the patents got me thinking. Is it possible that gallium (pronounced: Gal EE Yum), a simple mineral and nutrient could be a preventative for HIV and AIDS? So I posted the abstract to the Wikipedia page on HIV. It lasted less than a day until it was taken off by some really mean editor/censor. Why? It is a legitimate article, and apparently it was funded by the NIH. Why would someone remove it? Who are they defending? A pharmaceutical company or the public? I don't know, particularly since it doesn't seem to me that anyone has commercialized these patents or made any effort to teach this to the public.

MY GOAL: In this page, I will try to teach this material especially to the men and women who engage in anal sex, they being at extreme risk of HIV/AIDS. I believe that gallium nitrate should prevent HIV infection and AIDS when used topically (intra-anally and intra-vaginally), and hopefully save many lives. Also on this page are my recommendations for major increases in dietary zinc, since inadequate dietary zinc causes collapse and failure of the immune system identical to AIDS. For example, see this Google search for zinc and HIV, there are about 6 million pages listed.

ANAL SEX - TABOOS vs. PLEASURE vs. RISK: From antiquity to now there have been and are now various taboos, both secular, moral, legal and religious, that range from discouraging anal sex to laws prohibiting it (even between married couples) and even religious views that proclaim the participants will rot in hell. I suspect U.S. President Barack Obama is the first national leader to support anal sex, through his support for same sex marriage. Men and women have explored anal sex and found varying satisfaction with it, with views ranging from total disdain to it, to anal sex being the absolute ultimate in sexual pleasure. The anus has a high concentration of nerve endings and is an erogenous zone. This can make anal sex pleasurable for both the insertive partner and the receptive partner. In addition to nerve endings, pleasure from anal intercourse occurs due to the shared wall between the anus and the prostate for males, often resulting in erections and ejaculation. Females usually need clitoral finger stimulation in addition in order to climax. For a male insertive partner, the tightness of the anus can be a source of pleasure via the tactile pressure on the penis. This pressure can be much higher in men than women, since men have smaller pelvic openings than women.

Here is a link to a good anal sex "how-to-do-it" site. It is based upon the book on anal sex titled "Anal Pleasure and Health: A Guide for Men Women and Couples" by Jack Morin PhD. His book is considered by many to be the best book on the subject.

Perhaps the old taboos and disdain for anal sex result from the observation that the only God-given role of the anus is to expel feces and gas. Feces is a waste product of all living creatures and is nearly always held in disdain. Perhaps these views about feces extend to the anus. Anal sex has been practiced forever, and it is practiced world-wide in all cultures and nations, whether the leaders of those cultures, secular, political or religious, condemn it or not. Anal sex is practiced by both men and women of all ages, whether they be heterosexual, bisexual or homosexual.

If you think that anal sex is just for gay men, see this Center for Disease Control research report that shows that: "Among adults 25–44 years of age, 40 percent of men and 35 percent of women have had anal sex with an opposite-sex partner, and about 6.5 percent of men 25–44 years of age (90% of gays) have had anal sex with another man." Since women have strongly endorsed anal sex, it is here to stay and we need to consider the risks, as well as the rewards.

Anal sex is a very high-risk behavior for the infection of HIV and many other STDs including chlamydia, gonorrhea, hepatitis A, B and C, herpes and human papillomavirus. This essay only considers the risks of the Human Immunodeficiency Virus (HIV) infection, which is a permanent, life-long infection of the blood, all other bodily fluids including semen, and human genetics. Anal sex is the most likely sexual way to contract HIV infection, which leads to Acquired Immune Deficiency Syndrome (AIDS) which is eventually fatal.

This non-judgmental essay, for the first time, explores the potential for gallium nitrate (a potent anti-HIV agent) to prevent HIV infection by applying it in the anus, vagina or mouth at the time of the sex act.

IMPACT OF HIV/AIDS: What I do know is that people get acquired immune deficiency syndrome (AIDS) from the human immunodeficiency virus (HIV) and die within a few years of opportunistic infections from having an impaired CD-4 T-cell lymphocyte immune system and other immune system dysfunctions without treatment. The main cellular targets of HIV-1 are the CD4+ T-helper/inducer subset of lymphocytes, CD4+ cells of macrophage lineage and dendritic cells. HIV gets into cellular genetics, and becomes a permanent infection. The most prominent effect of HIV is its T-helper lymphocyte cell suppression and lysis effects. The CD-4 T-cell lymphocytes (thymus derived) are simply killed off or deranged to the point of being non-functional (they do not respond to foreign antigens). The destruction of CD-4 T-cells in the intestinal tract is far greater than in the peripheral blood. Since these cells orchestrate the entire immune system response to pathogens, we cannot live without them for long. The infected B-cell lymphocytes (bone marrow derived) cannot produce enough antibodies either. Thus the immune system collapses leading to the familiar AIDS complications. HAART does not restore CD4+ cells in the intestinal tract, even though it does in peripheral blood. People living with HIV are 60 times more likely than their peers to get non-Hodgkin lymphoma, a cancer of the white blood cells due to their low CD-4 counts. Interestingly, IV gallium nitrate is being formally tested for this disease. Another disease that is a complication of AIDS is tuberculosis, and gallium nitrate kills the bacteria (Mycobacterium tuberculosis) that cause it. If you want to know more about how HIV works, see this page. HIV can infect anybody, regardless of sex, age, ethnicity or sexual orientation.

MEN WHO HAVE SEX WITH MEN: Men who receive a penis (no condom) in their anus (bottoms) have an HIV prevalence 60-times higher than the general population, accounting for over fifty percent of all HIV diagnoses in the U.S.A.

This horrific data results mainly from bareback intercourse. This is because the anus and rectum (of both men and women) are 18 times more susceptible to infection by HIV infected semen than semen ejaculated into the vagina, and 36 times more susceptible than HIV infected semen ejaculated into the mouth in oral sex. This Center for Disease Control page indicates that oral sex is not a high risk way of transmitting HIV infection, unless there is tissue injury. It also shows the risks of numerous other potential means of transmitting HIV. Only specific fluids (blood, semen, vaginal secretions, and breast milk) from an HIV-infected person can transmit HIV. These specific fluids must come in contact with a mucous membrane or damaged tissue or be directly injected into the blood-stream (from a needle or syringe) for transmission to possibly occur.

Recent studies in HIV-1 infected individuals have demonstrated that the gastrointestinal (GI) tract is preferentially and profoundly affected during acute and chronic HIV-1 infection. Four studies provided estimates of the transmission risk for a single act of unprotected receptive anal intercourse. Pooling their data, the summary estimate is 1.4%. For long term multiple exposures between MSM partners, the risk of HIV transmission rose to 40%.

About one-fourth of all MSM in a study was infected with HIV, meaning their semen was also infected. Here is a Reuters article about the extremely high infection rate. Black MSM were twice as likely to have HIV infected semen (about half had HIV) than other MSM. Although MSM account for only about 2% of the U.S. population, they had over 50% of the known cases of HIV infection.

Much of the increased risk of HIV infection from anal penetration results from tiny tears and minor damage to the anus/rectum by the penis resulting in infection of blood. The main risk is HIV infection of the Peyer's patches in the immune system of the intestinal tract, which can be infected by HIV infected blood or semen. Regardless, tops should not be rough with bottoms since anal/rectum injuries very greatly increase the risk of HIV transmission.

A CLEAN RECTUM IS A HAPPY RECTUM: Feces should not be encountered in anal sex for an important reason. Feces is not smooth as it contains some tiny sharp particles from undigested food, usually bone. Therefore, feces can be abrasive and can cause tearing and damage to the rectum and anus during anal sex. This very greatly increases the risk of HIV transmission from the top to the bottom. Cleaning the anus/rectum may be accomplished by anal/rectum washing using some kind of lightly pressurized water source. A shower bidet is ideal. Use only warm water without any cleaning agents as they can harm the delicate lining of the rectum.

EJACULATING HIV INFECTED SEMEN INTO AN ANUS WILL RESULT IN HIV TRANSMISSION! This is why it is a state felony in 37 U.S. states for a person who knows he/she is HIV positive to have sex with another. Only about a quarter of infected MSM knew that their semen (and blood) were infected, thus the risk of spreading HIV from semen is extremely high. Perhaps some of these men knew they were HIV positive, but refused to say simply because they did not want to be seen as violating state laws. Receptive anal intercourse is the riskiest form of sex. In HIV infected men, even pre-cum -- the fluid before ejaculation -- contains HIV, so even if the inserter pulls out, infection is possible and likely. Men do get infected from both anal-receptive and anal-insertive sex, but anal-receptive sex is about 10 times more risky. HIV infected semen ejaculated into the anus/rectum carries a potential death sentence. On the other hand, protected anal sex (condom, auto-sex, or toy use) carries a low to non-existent risk. In American male gay couples, only about 45% are monogamous, thus HIV transmission rates are high.

The risk of HIV transmission from an infected partner through oral sex is much less than the risk of HIV transmission from anal or vaginal sex according to this CDC article. According to this article, the risk of HIV transmission through oral sex with a man is relatively low because the mouth is an unfriendly environment for HIV. Saliva contains enzymes that break down the virus and the mucous membranes in the mouth are much more protective than anal or vaginal tissue. However, any break in the mucous membranes of the mouth offers a perfect transmission route for HIV transmission. For HIV transmission to occur, the virus must get into the blood stream.

Estimates of HIV prevalence in the male to female transgender population range up to 78%, with race being a major factor. In the MTF group, African Americans showed the highest HIV seroprevalence (44%–63%), followed by Latinas (26%–29%), Whites (16%–22%), and Asian/Pacific Islanders (APIs) (4%–27%). Undoubtedly, there are some absolutely gorgeous, very well endowed lady boys.

With effective treatment, survival time after infection with HIV is roughly ten years, although after diagnosis of AIDS it is about one year. Although FDA approved drug treatments for AIDS and HIV can slow the course of the disease, there is currently no vaccine or cure. If there was a vaccine, then everyone taking it would become "HIV positive", without regard to whether or not they had HIV.

Researchers do not know with absolute certainty why the HIV epidemic has not spread to hetrosexual couples in the USA, but most suspect it is due to their high rates of monogamy. Some contrasting examples: In USA male gay couples, only about 45% are monogamous, and they have high rates of HIV/AIDS. African women are much less monogamous than American women, and they have much higher rates of infection than American women.

According to this Center for Disease Control report, there are no reports of lesbian HIV infection, unless there were other transmission factors (drugs, shared needles etc.) involved! This strongly suggests that the only sexual means of transmitting HIV to another is by infected semen.

Because of the devastation resulting from HIV/AIDS to the male gay community, it is mainly to MSM that I address this essay. What about gallium nitrate? It shows promise of preventing and treating HIV infection, which is extremely important considering that HIV will get into DNA if infection occurs and it will be permanent.

OUR GOAL: PREVENT INFECTION! A CASE REPORT OF GALLIUM NITRATE FOR HIV: A male HIV positive client who was treating his arthritis with gallium nitrate, told me in February of 2009 that before taking gallium that his CD4+ T-cell count was very low at < 200 cells/mm3). After taking gallium nitrate his CD4+ T-cell lymphocyte count rose to 2200, more than an 11-fold increase. This is consistent with the finding of Stapleton that Ga(III) prevented T-cell death.

His report is extremely important since it shows, for the first time, that gallium nitrate can increase peripheral blood CD4+ cells and have an undeniably beneficial effect on HIV/AIDS, although there was no discussion of intestinal CD4+ cell changes or viral titer. Had he not commented to me about this, nearly as a matter of fact, I would not have written this page.

GALLIUM NITRATE SAFETY: Is gallium nitrate safe for use in trying to prevent HIV/AIDS? I think so. People have been using low doses to treat arthritis and a number of other conditions for many years, and I have not heard of any safety related complaints. See my article on treating arthritis with gallium nitrate here. I have used it frequently to treat my own old-man aches and pains. I think that the risk of too much gallium in the blood is similar to getting too much of any mineral, since they can displace each other. Perhaps one should take large dietary supplements of calcium, iron, zinc and magnesium to compensate. The blood level of gallium said to be anti-HIV (100 micromolar) is the same as the high end of normal blood level (100 micromolar) of zinc.

The 1% gallium nitrate solutions are 345-micromol ionic Gallium solutions, which kills essentially 100% of HIV. Here is a 2010 review of medical uses of gallium and toxicities.

Most importantly, gallium nitrate should never be used with drugs that are known to harm the kidneys (e.g., gentamicin and amphotericin B) because of the increased risk for severe kidney problems. Overdose symptoms may include nausea and vomiting, or urinating less than usual. Thorough hydration (lots and lots and lots of drinking water) is a good antidote to gallium overdose. That is one reason we always mix it in lots of water.

CONCENTRATED GALLIUM NITRATE: The 42% gallium nitrate solutions that we market contain 57,000-milligrams of elemental gallium per each half-liter bottle. The product is sufficiently concentrated that it feels "oily" and is quite slippery on the skin. This feeling of oiliness on the skin must not be confused with any sex lubricant value, because it is not there. The pH of the 42% gallium nitrate product is 1, even though it is highly buffered by gallium (III). Since the pH is so low, it would be highly injurious to delicate anal/rectum or vagina/cervix tissues. Diluting 42% gallium nitrate solutions to 1% solutions raises pH to pH 3 to 4. Gallium nitrate can be stored in any glass or plastic (non metallic) container and it should be kept sealed to protect against evaporation, since evaporation (including gallium nitrate on towels and tissues) can produce much stronger, potentially harmful concentrations. The 1% gallium nitrate solutions do not cause pain or appear to be harmful to the mouth, penis, anus/rectum or vagina/cervix, however it has not been formally tested in clinical trials or any other formal setting.

HOW TO MAKE ONE PERCENT GALLIUM NITRATE SOLUTIONS:

• Obtain 42% gallium nitrate solutions over the Internet by Googling "42% gallium nitrate" without the quotation marks.
• To make a 1% gallium nitrate solution add 12-ML of the 42% gallium nitrate solution to 500-ML (a pint) of distilled water.
• This creates a working stock or a supply for later use in much smaller volumes as described below.

ORAL USE: For oral use (including swallowing) gallium nitrate solutions should not be stronger than a 1% aqueous solution (volume basis). The 1% gallium nitrate solutions are 345-micromol ionic Gallium solutions, which kills essentially 100% of HIV. The daily human dose of the 1% solution would be 50 to 100 CC of the 1% solution. This solution will make the mouth feel dry. One can hardly slide the tongue or penis around in the mouth due to lack of salivary lubrication by gallium nitrate, consequently it should best be used after oral sex. Do not regularly exceed consuming 100 CC of the 1% gallium nitrate solution per day. Remember that the gallium must contact the virus and that boluses of semen in the mouth need to be broken up (by rapid mouth swishing and/or spitting it out) while the gallium nitrate is in the mouth. That will help assure full contact with the virus and their demise. The 1% solution has been used orally in many thousands of people (mainly in treating arthritis). Considerably stronger solutions (over 5% gallium nitrate) can cause increasingly severe oral pain. After oral sex, wash the mouth with the 1% gallium nitrate solutions for about 15 minutes, and slowly swallow it (no more than 100 to 150-CC) as a semen chaser in an effort to directly inhibit replication of HIV in the swallowed semen.

TOPICAL GALLIUM NITRATE WASHES: Topical anti-HIV "after sex" washes for the penis, vagina/cervix and anus/rectum can be prepared in the same manner as for oral use. The 1% gallium nitrate solutions are 345-micromol ionic Gallium solutions, which kills essentially 100% of HIV. Intra-anal doses of the 1% gallium nitrate solutions are usually in the 50 to 100 CC range.

Used topically in the anus (and vagina), the anti-HIV gallium nitrate solutions will be used and absorbed exactly where it is needed to try to prevent HIV infection from infected semen. Washing the penis is straight forward, while washing the vagina/cervix and anus/rectum would respectively require douching and anal syringes. An anal syringe can deliver gallium nitrate solutions past the anal sphincter and into the rectum.

Due to the extreme risk of HIV infection originating in the gastrointestinal tract (60-times any other means) from infected semen, anally introduced 1% gallium nitrate solutions should be left in the rectum. Every effort must be made to keep the solutions in the anus/rectum or to replace it if it "leaks" out the anus. Perhaps the best time to treat the anus/rectum with the 1% solutions (immediately after sex) would be at bedtime or other times when the person will be recumbent. An anus-up position would be helpful to retain the solution in the event of anal dilation or prolapse. Remaining recumbent for hours helps prevent leakage. What has been said here generally applies to the vagina/cervix also, although the risk of transmission is sufficiently reduced that simple rinsing and keeping the vagina wet with the 1% gallium nitrate solutions for about 15 minutes should suffice.

A 50 ML anal syringe will deliver the proper amount of the 1% solution of gallium nitrate. Don't overdose, but perhaps a second and even a third application during or after anal sex would be well advised, especially if there is anal leakage.

Remember that my main point in using gallium nitrate is to try to prevent HIV infection at the source (anus, rectum, mouth, vagina), since it seems best to remain free of HIV infection so that it does not need to be treated later. Remember that HIV infection is permanent!

Gallium nitrate - in the concentrations used here - is also bacteriostatic to all iron dependent bacteria, which excludes the beneficial gastrointestinal bacteria, since none of which are iron-dependant. Had gallium been harmful to intestinal bacteria in horses, they would have become colicy, but none have ever had an intestinal issue from gallium nitrate. Neither have people using gallium nitrate for arthritis or other illnesses such as Lymes or Chron's diseases. About 80% of all pathogenic (harmful) bacteria and fungi are killed by gallium nitrate solutions. Actually, gallium can be more accurately thought of as a "birth control" agent for iron-dependent bacteria and fungi, and they die-off naturally - not from gallium toxicity. Consequently, they never become resistant to gallium. The bacteria and fungi see gallium as if it were iron, and they use it as if it were iron. Unfortunately for the bacteria and fungi, gallium (III) will not become gallium (II), while iron (III) will become iron (II), and the bacteria cannot replicate. Look at the list of iron dependent bacteria above, since some of them are found in female urinary tract infections.

SEX LUBRICANTS: PRO-HIV OR ANTI-HIV? A recent medical research study of popular over-the-counter and mail-order sex lubricants showed that the majority were found to be toxic to anal and rectum cells and tissue, apparently rendering MSM more vulnerable to infection of HIV and other sexually transmitted diseases. According to the article, two of the six lubricants, PRE and Wet Platinum, were shown to be safest for the cells, while Astroglide was the most toxic to anal and rectum cells and tissue. KY Jelly had the worst effect on rectal bacteria, essentially wiping out the entire colony. ID Glide and Elbow Grease had intermediate effects, the research team found. None of the lubricants was found to have measurable anti-HIV activity. Another study, showed that glycerin and the thickener polyquaternium-32, common ingredients in personal lubricants, had anti-HIV properties. A 2001 University of Texas study showed that three sex lubricants (Astroglide, Vagisil and ViAmor) are highly active against both HIV-infected leukocytes suspended in seminal fluid and active against cell-free HIV, under in vitro conditions that simulate in vivo conditions. A 2004 University of Texas study showed that Astroglide, KY Liquid, Replens, Vagisil, ViAmor, and Wet Stuff, each containing active ingredients identified as glycerin and polyquaternium-32 were anti-HIV in vitro. Those studies are countered by this 2011 study, which shows that Astroglide Liquid, Astroglide Warming Liquid, Astroglide Glycerin & Paraben-Free Liquid, and Astroglide Silken Secret, significantly enhanced HIV-1 replication (p<0.0001). This 2012 report suggested that some lubricant products may increase vulnerability to STIs, including HIV. Consequently, researchers have worked on reformulating a vaginal sex lubricant to be safe for anal sex. A reduced glycerin anti-HIV product for both vagina and rectum use - Tenofovir Vaginal Gel - appears effective in protecting cells against HIV and does not damage rectal cells according to this article. I suggest that if any of these water-based lubricants repeatedly cause distress, such as excessive gas and/or diarrhea, such should be interpreted as harm by the product, and another type of lubricant should be tried.

ANAL SEX LUBRICATION SEEMS VITAL: Some form of lubrication is vital for anal sex. One should not depend totally on spit, pre-cum, semen and anal mucous for lubrication. If anal tearing, even the tiniest amount, results from insufficient lubrication, such provides the vital route for HIV to be transmitted. This is the main reason for the top to go slow and not cause pain (and tearing) for the bottom. Pain relief ointments should not be used, so that the bottom can readily determine if there is likely to be injury, since pain predicts injury. Safe sex lubricants for anal use are silicone and glycerin. The disadvantage of the glycerin and water personal lubricants is that they dry out with continued use, and they have mixed reviews on their effect on HIV.

The choice of lubricants remains an unsettled questions, and Tenofovir Vaginal Gel - again appears effective in protecting cells against HIV since it is water-soluble and will not prevent gallium ions from killing HIV.

THE EASY WAY OUT: Why bother making an anti-HIV anal wash when condoms would do the same thing, that being prevent transmission of HIV? CONDOMS ARE VASTLY PREFERED! But, amature gays have rejected condoms for the most part. Why? Rejection of condoms in the MSM community resulted from the MSM attitude towards HIV/AIDS of, "Oh! What the hell, there are medicines that take care of HIV/AIDS." If anyone is interested, twenty-four hour tests of Trojan® non-lubricated rubber condoms show that gallium nitrate solutions do not harm them. I will let others promote celibacy and condoms. However, I will mention that the statistical odds of being exposed to HIV through unprotected anal MSM sex is the same as being shot while playing Russian roulette with a revolver. Remember, the Grim Reaper rides bareback.

COMPLICATIONS AND SIDE EFFECTS OF HAART DRUGS: Have you thought about the complications and side effects from HAART drug treatment for AIDS? Did you know that about 25% of HIV patients stop therapy within the first year on HAART drugs because of side effects? What happens to them? I suspect they have a miserable death. Would you really enjoy the following complications and side effects for the rest of your life? Some common side effects of HAART medicines include nausea, vomiting, diarrhea, liver failure, skin rashes, swelling of the face, lips and tongue, kidney stones, anemia, peripheral neuropathy (chronic pain), pancreatitis, myelosuppression (decreased bone marrow production of red blood cells, white blood cells and platelets), increased cholesterol and triglycerides, cardiovascular disease, rapid aging, suicide, diabetes, depression, dizziness, abdominal pain, insomnia and ugly "fat pads". Did you know that up to 75% of all HIV/AIDS patients develop vision problems, with about 20% becoming totally blind? Here is a 1996 medical journal article that lists side effects of some of the HIV drugs. There are too many to list here. Read the article NOW! Educate yourself about side effects. Look through this Google search for "HIV medicine" and "side effects", and this Google search for "HAART" and "side effects". HIV/AIDS is a jackpot for physicians and hospitals. What about the new "preventive" drug for HIV, Truvada? Look at the side effects listed on their site, and ask yourself if using condoms and/or gallium nitrate is a better idea. The list is long, but includes thinning of bones, nausea, vomiting, muscle pain, and/or weakness, kidney problems, diarrhea, dizziness, nausea, headache, fatigue, abnormal dreams, sleeping problems, rash, depression, vomiting, inflammation of the pancreas and liver, allergic reaction, shortness of breath, pain, fatty liver, stomach pain, weakness, indigestion, and intestinal gas and other deleterious effects.

CAVEATS, CONCERNS, WARNINGS and MISCELLANEOUS THOUGHTS: Although there is no doubt that 1% gallium nitrate (or stronger) is anti-HIV, the wise person would use a condom for all anal sex. They are as near 100% fool proof as anything. Ideally, they would be used with gallium nitrate solutions. Although gallium nitrate may be useful in preventing (or treating) HIV infection by stopping the replication of the viruses, thus potentially preventing AIDS when used intra-anally, there is no guarantee that 100% of the HIV viruses will be killed by Gallium since it must directly contact the virus. I am certain that results will vary, depending upon the skills and habits developed.

Please remember that this essay tries to suggest ways to PREVENT HIV infection, not treat it. It is my contention that it is best to try to "PREVENT" it with topical washes, especially of the anus, since it is over 60-times more likely to become fatally infected with HIV than any other tissue. See the Stapleton patent for details on "treating" HIV with gallium nitrate. All in all, it seems to me that anal sex is risky business. Clearly, HIV infection can terminate the health, wealth and lives of many otherwise innocent and healthy people. It really makes money for doctors and hospitals. Do we want that? I say NO!

TREATMENT OF EXISTING HIV INFECTION AND AIDS Although this essay is primarily about preventing infection, treatment of HIV/AIDS remains a very important issue. Remember from above that a male HIV positive client who was treating arthritis with gallium nitrate, told me that before taking gallium his CD4+ T-cell count was very low at < 200 cells/mm3). After taking gallium nitrate his CD4+ T-cell lymphocyte count rose to 2200, more than an 11-fold increase. Treating HIV orally apparently killed his HIV, allowing the T-cells to return to a normal level. This is the main goal of HIV treatment, to kill the virus and increse the T-cell counts back to normal so that the immune system function is restored, thus preventing or curing AIDS. What would be the dosage of oral gallium nirate solutions? I suggest the same as the doses that are suggested to prevent HIV in oral sex, which is 50 to 100 CC of the 1% solution daily. The 1% gallium nitrate solutions are 345-micromol ionic Gallium solutions, which kills essentially 100% of HIV. These solutions become greatly diluted when they are absorbed into the blood, yet efficacy appeared anyway; which is to me somewhat surprising. If we add increasing zinc intake as described in this section, HIV and AIDS should be completely defeated. If gallium nitrate is stopped, will the HIV return? That is unknown, but unlikely due to the extrodinarily high kill-rate. What if zinc treatment is stopped (without gallium treatment)? There is evidence that the AIDS will return. Regardless, 50 to 100 mg of znc is important to prevent a wide variety of disease and is otherwise harmless, so it should be taken daily for the remainder of ones life.

Concerning the possibility of criticism of this extremely early and essentially uncontrolled research, I quote Albert Einstein who said, "If we knew what it was we were doing, it would not be called research, would it?"

Consequently, I would appreciate anecdotes/case histories (diagnosis, previous treatment, results of previous treatment, effects from gallium and zinc, records of results, especially CD-4 counts, side effects, various records of opportunistic infections related to HIV) for publication as a testimonial below. I will also publish constructive comments and questions. Your e-mail address on the testimonial would add credibility. Confidential email addresses are available through Hotmail, Gmail and others. If gallium does work as expected, I will write up the collected results (protecting confidentiality) for submission to a medical journal. Not that they would publish it! Heaven forbid! A cheap and effective nutrient preventative for HIV and AIDS? The pharmaceutical companies would have me shot!

ON YOUR MARK, GET SET, GO! I will publish below the exact words (testimonials) of anyone that tries gallium nitrate as a preventative for HIV and/or AIDS. I am most interested in experiences using the anal route, since that has the potential to stop HIV infection in its tracks in the most people. Are there sex lubricants that work well with gallium nitrate? Have you tried Mentholatum or Vicks as sex lubricants? They should be wonderfully titillating and erotic. Although prevention is very important to the gay man and gallium nitrate can be used now, only carefully controlled, large scale clinical studies would be convincing to the medical profession.

CASE NOT CLOSED:

• Did you know that not everyone agrees that HIV causes AIDS?
• Did you know that the evidence is completely missing?
• Did you know that Nobel Prize winner Kary Mullis thinks that the whole thing is a scam? Read Chapter 18,"Case Not Closed", from his book "Dancing Naked in the Mind field" here, wherein he debunks the entire notion of HIV causing AIDS.
• Did you know that many of the old "War on Cancer" researchers just needed something else to work on? So they invented the notion that one of the retroviruses, HIV, caused AIDS.
• Did you know that no one really knows what causes AIDS? I think I do. Read further about zinc deficiency and its horrible effects on the immune system.
• Did you know that the cause of AIDS could be a simple zinc nutrient deficiency?

DON'T FORGET ZINC FOR HIV/AIDS! I very strongly suggest taking zinc (100 to 150-mg/day of a zinc from zinc gluconate dietary supplements initially for several weeks to restart the T-cell lymphocyte system. After the initial several weeks high dose, lower the dose to 50 mg zinc (as zinc gluconate) and keep your zinc blood levels in the high normal range (as determined through a blood clinic). See my 1994 article about zinc for HIV/AIDS here for an explanation of why this recommended initial dose (100 to 150-mg) is so much stronger than the tiny doses that "nutritionists" recommend. Zinc deficiency is defined by nutritionists as being less than 11-mg zinc per day in men.

ZINC VITAL TO IMMUNE SYSTEM: Less than 11-mg zinc daily turns off the T-Cell lymphocyte system, just like the HIV virus. Zinc is an absolutely essential nutrient for the T-cell lymphocyte system, and large amounts are required to re-start this thymic lymphocyte system once it is down. Without an over-supply of zinc (100 to 150-mg zinc daily for several weeks) to re-start the T-cell lymphocyte system, it will remain turned off. Ominously, gestational zinc deprivation in mice causes persistence of immunodeficiency for three generations. Consider our progeny with permanently impaired immune systems from inadequate dietary zinc. Sometimes large amounts of zinc cause nausea, so take it in small frequent doses throughout the day and evening. Also, consider the enormous need for zinc in semen below.

On the other hand, too much zinc, 300-mg per day, in young people (without HIV/AIDS), was immuno-suppressive according to this 1984 article. Be careful with extra dietary zinc, and have your serum levels of zinc tested by a clinic on occasion. You want blood levels at the high end of the "normal" range (around 110 micrograms/dl), and not higher. You can get blood testing done without a physician's prescription at AnyLabTestNow offices nation-wide.

ZINC VITAL TO TREAT HIV/AIDS: Zinc has been shown to be vital in the treatment of HIV and AIDS. See this very important article titled "Zinc deficiency profoundly increases risk for HIV-1 related mortality". Also see this similar report. Examine the relationship between zinc and HAART drugs here. Examine the relationship between HIV and zinc here. Examine the relationship between AIDS and zinc here. Zinc deficiency causes AIDS-like immune suppression, consequently having low blood zinc and HIV infection is a double-whammy to the immune system, and it is a one-way, pre-paid ticket to a quick death. Take your zinc!!!

ZINC FOR DIARRHEA: In this HIV/AIDS study, zinc supplementation (only 15 mg/day!) for 18 months reduced 4-fold the likelihood of immunological failure. Zinc supplementation also reduced the rate of diarrhea by more than half compared with placebo. In my opinion, that was not nearly enough zinc! Controlling diarrhea caused by HIV/AIDS is vital if one is to live.

IS ZINC DEFICIENCY THE CAUSE OF AIDS? It may be that inadequate dietary znc is the main cause of AIDS and related AIDS-like symptoms. See this warning page on the symptoms of zinc deficiency. I wrote that page many years ago, and people still don't realize that there is so little zinc in our diets that we are all becoming increasingly susceptible to AIDS. There is absolutely no doubt that inadequate dietary zinc, specifically when considered relative to the large amount of zinc ejaculated daily by some men, will cause AIDS-like immune suppression and possibly early death.

ZINC AND THE IMMUNE SYSTEM REVIEW: If you are a scientist or physician, you may be interested in the nearly 4000 peer reviewed medical journal articles on "zinc" and "immune system" found here. However, for time constraint reasons, I would start the research with those articles written by Ananda S. Prasad MD, PhD, the father of human zinc biochemistry at Wayne State University in Detroit, Michigan, found here.

LEAST DIETARY ZINC IS IN AFRICA: The notion of low dietary zinc as the cause of AIDS also greatly explains the incidence of AIDS in Africa, a continent that has the lowest dietary zinc intake of the entire planet and the highest incidence of AIDS. Click here to see a map of the world by zinc dietary status, and here for a slightly different version. To see the webpage on "zinc and smallpox" in which these maps are found click here. Compare these "zinc in diet" maps with the incidences of AIDS by nation in this page. Notice that there is a good correlation, and that correlation plus the comments by Kary Mullis are why I think HIV-induced zinc deficiency is the real cause of AIDS. Fifty-mg of zinc/day everyone?

ZINC AND SEX: Inadequate dietary zinc causes major sexual functional problems, as shown in this medical journal article. Serum testosterone concentrations, seminal volume, and total seminal zinc loss per ejaculate are sensitive to short-term zinc depletion. Each ejaculate uses 0.5 to 1.5-mg of zinc (100 to 300-mg zinc/liter semen). Compare the amount lost per ejaculate with the RDA for zinc, which is around 11-mg per day. The American diet and the diet of most countries only contain about 10 to 12-mg of zinc, yet if the daily intake falls even a few milligrams lower, then zinc-deficiency induced AIDS can develop.

To avoid AIDS from inadequate zinc in the sexually active person, I suggest taking 50-mg of zinc per day (after an initial 100 to 150-mg dose per day for a month), since zinc also stabilizes and protects plasma cell membranes from damage by microbes (such as viruses) and other cytotoxic agents as shown in this article.

ZINC FOR HERPES SIMPLEX (1 and 2): In 1985 I wrote a review of many medical journal articles that showed that solutions of zinc gluconate, zinc sulfate, zinc chloride and zinc acetate (the ionizable compounds of zinc) were strongly anti herpes. They killed herpes viruses topically, on the skin, as they came up from the nerve ganglia. It is a long-term treatment and it should be thought of as laying a "trap" for the virus on the skin. When they come up they contact the zinc and die. Eventually, the nerve ganglia becomes depleted and the infection is over. See this page for details and the published article.

NUTRITION FOR A HEALTHY IMMUNE SYSTEM: No one knows more about nutrition and the immune system than the highly regarded RK Chandra in Canada. Here is one of his abstracts: "For millennia, food has been at the center of social events, in times of joy and in times of sorrow. Protein-energy malnutrition is associated with a significant impairment of cell-mediated immunity, phagocyte function, complement system, secretory immunoglobulin A antibody concentrations, and cytokine production. Deficiency of single nutrients also results in altered immune response: this is observed even when the deficiency state is relatively mild. Of the micronutrients, zinc, selenium, iron, copper, vitamins A, C, E and B6, and folic acid have important influences on immune responses. Overnutrition and obesity also reduce immunity. Low-birth-weight infants have a prolonged impairment of cell-mediated immunity that can be partly restored by providing extra amounts of dietary zinc. In the elderly, impaired immunity can be enhanced by modest amounts of a combination of supplemental micronutrients. These findings have considerable practical and public health significance. See his full report here. In this 1999 article Chandra reported that inadequate dietary zinc causes profound suppression of immune response.

CAN HIV DO GOOD? Believe it or not, an inactivated form of HIV has been recently used to cure lymphoblastic leukemia in a child. The inactivated form did not and will not cause her to be HIV positive. Read the story here.

NATURE RULES! It is interesting to me that zinc (element 30) and gallium (element 31) are immediately next to each other on the periodic table of the elements, and that they both have beneficial effects on HIV and/or AIDS. What will Nature think of next?

You are on your own, best wishes.

George Eby
George Eby Research Institute
Austin, Texas
Telephone 1-512-263-0805
george.eby@george-eby-research.com

I dedicate this essay to my son, Colin Martin Eby, who was gay and died at age 32 on May 14, 2011.

TESTIMONIALS

Hi George,

I have been using 50CC of a 1% gallium nitrate solution made from your 42% gallium nitrate product (that I found on the internet) after each MSM encounter for over a year. I use it on myself and my partners. Recently, I had bareback sex with a man with a really big, very hard cock and he hurt me (far too rough/brutal). I made him stop and I nursed my little anus with Mentholatum Ointment (feels really good). For some reason, I did not use gallium nitrate, perhaps because he had not ejaculated in me. Immediately after that, I noticed anal bleeding every time I checked my anus with my finger, and blood on toilet paper every time I wiped. This went on for about a week. I am on Warfarin (Coumadin), so my blood is quite thin. I avoided sex for over a week, nursing my bleeding anus. One day, I met a man that I thought was perfect and we had a deep and meaningful (bloody) bareback sexual relation. He fucked my anus until I thought I was going to pass out! Neither of us cared about the blood, and it actually seemed to stimulate us even more. Immediately after that, I used the 1% gallium nitrate solution (50 CC) intra-anally as a precaution against HIV. That was at bedtime, and I slept like a baby. I did awaken once to pee, and I decided to wipe my ass to see what I could see. I noticed a bit of blackish-red blood. In the morning I went to poop, expecting more blood, but I noticed no blood at all! I was thrilled! Even after a week and some really good loving, no more anal bleeding. I used gallium each time. George, is it possible that gallium nitrate stops bleeding? If so, I will have two very good reasons to always use 1% gallium nitrate after anal sex. No, that's not right, I will have three or four good reasons if I include anti-bacterial and anti-fungal effects of gallium nitrate. There is no telling what microbial junk these pretty-boys introduce into my anus! Thank you!!! BTW, my T-cell count remains normal, and my whole immune system seems normal too, with no evidence of HIV according to multiple blood tests. I also take 50-mg of zinc daily.

Thanks, Billy B.

Hi Billy,

You were right to avoid sex while bleeding, it would be a perfect way to transmit a disease, especially HIV, from another to you, even though your own feces is very unlikely to do so according to a proctologist I know. Also, remember that gallium ion (like found with gallium nitrate) is bacteriostatic to nearly all pathogens. I had not heard of an anti-bleeding effect of gallium before, so I checked the medical literature. There is a very recent (2011) medical journal article that describes the ability of gallium nitrate (my 14% solution) to stop bleeding rapidly compared with controls. It did not refer to anal bleeding, butt... See the article here. I remember one of those scientists since he bought the gallium nitrate from me. Interestingly, it worked on both Warfarin and non-Warfarin treated subjects. They noticed a blackish-red (brown) clot too from use of gallium. They used 14% solution topically, but a 14% solution intra-anally would cause significant anal discomfort/pain. Please remember that their report is the only published information on the matter. I am impressed and pleased that your use of a 1% solution was effective. I don't see any risk from using 50 CC of 1% gallium nitrate solution(s) to stop anal bleeding, especially since the 1% solutions intra-anally are in general use to try to prevent HIV transmission. Also, remember that gallium is highly bacteriostatic to iron dependant bacteria (this excludes intestinal bacteria because they are not iron dependant); so all in all, it appears good for the anus and rectum.

Incidentally, a man recently reported that he used 14% gallium nitrate to stop bleeding on a penis that has started to bleed (from an injury sliding/falling off the gurney) severely immdiately after a circumsision. He reported that the gallium nitrate made a large and very hard "blood clot" on each suture causing local pain over the following several weeks as the circumcision healed. Apparently gallium nitrate should not be used on "sutures".

NOTE: By spring of 2012, I have now had several men tell me by phone that they had HIV/AIDS with very low T-cell counts and that after regular use of intra-anal and oral gallium nitrate, their T-cell counts had normalized (increased 10 to 12-fold) and they felt much better. I have no knowledge of changes in their intestinal T-cell counts, but anal gallium has a real chance of working. Unfortunately, I have no further data or ability to confirm their comments.